Essais thérapeutiques

Saline Hypertonic in Preschoolers + CT

Etude : Hypertonic Saline
Type d'étude : Modulateur du CFTR
Titre : Saline Hypertonic in Preschoolers With Cystic Fibrosis and Lung Structure as Measured by Computed Tomography (CT)
Phase : 2-3
Promoteurs :

Age : 3-5 years
Lien internet : https://clinicaltrials.gov/ct2/show/NCT02950883

EMPIRE CF: A Phase 2 Study to Evaluate the Efficacy, Safety, and Tolerability of CTX-4430 in Adult CF Patients

Etude : CTX-4430
Type d'étude : Modulateur du CFTR
Titre : A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy, Safety, and Tolerability of CTX-4430 Administered Orally Once-Daily for 48 Weeks in Adult Patients With Cystic Fibrosis
Phase : 2
Promoteurs :

Age : 18 Years to 30 Years
Lien internet : https://clinicaltrials.gov/ct2/show/NCT02443688

Rollover Study to Evaluate the Safety and Efficacy of Long-term Treatment With Lumacaftor in Combination With Ivacaftor

Etude : Ivacaftor, Lumacaftor
Type d'étude : Modulateur du CFTR
Titre : A Phase 3, Rollover Study to Evaluate the Safety and Efficacy of Long-term Treatment With Lumacaftor in Combination With Ivacaftor in Subjects Aged 6 Years and Older With Cystic Fibrosis, Homozygous for the F508del-CFTR MutationA
Phase : 3
Promoteurs :

Age : 6 Years and Older
Lien internet : https://clinicaltrials.gov/ct2/show/NCT02544451

Study of GLPG1837 in Subjects With Cystic Fibrosis (G551D Mutation) (SAPHIRA1)

Etude : GLPG1837
Type d'étude : Modulateur du CFTR
Titre : A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy, Safety, and Tolerability of CTX-4430 Administered Orally Once-Daily for 48 Weeks in Adult Patients With Cystic Fibrosis
Phase : 2a
Promoteurs :

Age : 18 Years and Older
Lien internet : https://clinicaltrials.gov/ct2/show/NCT02707562